Juvenile Pemphigus Vulgaris
نویسنده
چکیده
Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin and mucous membranes that affects older individuals. The disease rarely affects children and adolescent patients. The first manifestation of PV appears in the oral mucosa in the majority of patients, followed by cutaneous lesions. The diagnosis is based on clinical findings and laboratory analyses, and it is usually treated by the combined administration of corticosteroids and immunosuppressants. Dental specialists must be proficient to recognize the clinical features of PV to ensure early diagnosis and treatment, so that it determines the favorable prognosis and course of the disease. This article reports a case of juvenile PV.
منابع مشابه
[Juvenile pemphigus vulgaris].
BACKGROUND Pemphigus vulgaris is a rare autoimmune blistering disease seen only, rarely, in children. CASE-REPORT Two young girls, aged four and 15 years respectively, presented with oral and/or cutaneous blisters (case 2). The diagnosis of pemphigus vulgaris was confirmed by histology (suprabasal acantholysis) and immunopathological analysis (direct and indirect immunofluorescence, antidesmo...
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Systemic corticosteroids are the treatment of choice for pemphigus vulgaris. Immunosuppressive agent (azathioprine, cyclophosphamide) could be added for patients with severe disease that cannot be controlled by corticosteroids alone or to reduce the dose of corticosteroids.[5] However, immunosuppressants continue to have the complications of systemic infections. Successful use of rituximab ther...
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INTRODUCTION Pemphigus vulgaris (PV) is a chronic and infrequent autoimmune mucocutaneous disease that is characterized by the loose blisters and erosions on the skin and mucous membrane. Middle-aged adults are affect most frequently and the elderly and juvenile cases are infrequent. Herein, we reported a case of pemphigus vulgaris in an elderly patient. CASE PRESENTATION We reported a case o...
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Pemphigus vulgaris (PV) is a chronic, autoimmune, intraepidermal blistering disease of the skin and mucous membranes. The initial clinical manifestation is frequently the development of intraoral lesions, and later, the lesions involve the other mucous membranes and skin. The etiology of this disease still remains obscure although the presence of autoantibodies is consistent with an autoimmune ...
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